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Description

Recognition and receptor-mediated endocytosis of the lysosomal acid lipase secreted by cultured human fibroblasts

Some people notice improvements within days to a couple of weeks when deficiency is present

Then, 12.5 mmol sodium hydroxide (NaOH) solution was dropwise added into the suspension to bring the pH above 12 and oscillated for 5 h at room temperature

Therapeutic efficacy depends on optimal integration of target antigen selection, antibody format, linker stability, payload potency, and conjugation chemistry ( Figure 1 )